Acanthosis Nigricans (AN) as a possible marker of an increased risk for diabetes. To determine the prevalence of AN in type 2 diabetes mellitus (T2DM) and it correlation with obese women with Polycystic ovary syndrome (PCOS) and Body mass index (BMI) in Central Indians. Present work is a cross sectional open label study carried out over a period of 11 months in tertiary level hospital in Central India. A total 300 patients with T2DM were included in the study. Who were age between 18-50 years. Regression analysis was done to determine the association of AN with T2DM.AN was observed in 150 of the T2DM patients. BMI was significantly higher in the T2DM patients with AN as compared to those without AN. Among the obese PCOS patients 81% had BMI value of more than 30 kg/m2 as compared to 13% of the patient who did not have AN. AN is correlated with obesity.Central Indians have high prevalence of AN and it is an independent cutaneous marker of both T2DM and BMI.
