Multimodal Instructional Method (MIM) has been successful used as an effective gender responsive instructional method for actively learning of chemical bonding in Chemistry by both male and female science teacher trainees in the College. Learning of chemical bonding and the mode of instruction are not only one of the most identified concepts that posed difficulty for students to learn, but scare most of the students especially female students to study science. This paper examine the effectiveness of the use of Multimodal instructional Method to teach chemical bonding and the effect on learning needs female and male students. The results of 60 college students which comprised of 30 female and 30 male students confirmed that the method created active learning for every student.The MIM improved deeper conceptual understanding of chemical bonding, catered for differences learning styles of both male and female. Most importantly, the method made female students developed interest to study the subject, and also motivated them to become science teachers.
