The plant extracts of Cyathea nilgirensis were evaluated for anti-inflammatory activity in mice using the carrageenan induced-paw edema test. The study has shown that the ethanol and chloroform extracts of plant C. nilgirensi possess a significant anti-edematogenic effect on paw edema induced by carrageenan. Both the extracts of C. nilgirensis showed significant (p≤ 0.001) decrease in edema with a percentage of inhibition ranging from value 13.71 ± 1.25 to 7.15±1.52 at 100mg/kg in chloroform extract and ethanol extract showed values ranging from 13.86 ± 2.12 to 6.7±2.64 at 100mg /kg. These extracts have shown better results compared to standard drug diclofenac sodium. This study revealed the promising anti[1]inflammatory activity of C. nilgirensis which has been carried out scientifically for the first time. The evaluation could be an important finding globally, as inflammation has become a common disease. Hence the results of this study indicates that C. nilgirensis can be effective remedy in acute anti-inflammatory disorders.
