Antisynthetase Syndrome-A Case Report

Dermatomyositis is a subtype of idiopathic inflammatory myopathies, characterized by cutaneous involvement and proximal muscle weakness. It can also have other systemic manifestations like arthritis, pulmonary and cardiac involvement. Antisynthetase syndrome is a rare variant with myositis and interstitial lung involvement characterized by autoantibodies against aminoacyl-tRNA synthetases. Here we present a case of dermatomyositis with predominant interstitial lung disease (ILD) anti-aminoacyl-tRNA synthetase antibodies (antisynthetase syndrome).