Introduction: Cancer is a unique disease characterized by abnormal growth of cells which have the ability to invade the adjacent tissues and sometimes even distant organs. In India, oral cancer accounts for about 40 % of all cancers of the body and is a major public health problem, emerging as a killer disease. Cancer in all forms accounts for around 12% of the deaths throughout the world. India has one of the highest incidences of oral cancer in the world. Aim: To evaluate the association if any between ABO blood groups and oral cancers. Methods: Study was conducted at Mahavir Cancer Sansthan, Patna. It comprised of 300 oral cancer patients and 800 controls. Chi square test and odds ratio were used to assess the association between ABO blood groups and oral cancers. Results: It was found that people with blood group A had higher risk of developing oral cancers when compared to people of other blood groups. Conclusion: It was observed that different blood group have been associated with oral cancers and blood group A has more predilections for developing oral cancers.
