Association Between Diabetes Mellitus And Hypothyroidism And Its Co Relation To Dyslipidemia In Patients Attending A Tertiary Care Hospital

Research Article
Amandeep Kaur
DOI: 
http://dx.doi.org/10.24327/ijrsr.2018.0907.2366
Subject: 
science
KeyWords: 
Thyroid disorders; Type 2 diabetes mellitus; Dyslipidemia
Abstract: 

Background: Diabetes Mellitus and hypothyroidism are major endocrine disorders leading to secondary disorders. Hypothyroidism and Type2 (T2DM) diabetes are both associated with increase in triglyceride levels. Here, our study was conducted in region around Gian Sagar Medical College and hospital and we found the typical cases of type2 diabetes mellitus and hypothyroidism i.e. elevated TSH, FBS and TG levels. Objectives: The study aimed at determining the incidence and prevalence of thyroid dysfunction in patients with T2DM and dyslipidemia in relation to age, sex, metabolic syndrome and other comorbid conditions. Research designs & methods: In this observational cross-sectional study, total 200 subjects were enrolled aged between 40 and 75 years in which 100 were control subjects (group A) and 100 were Type 2 DM patients (group B). Both the groups were evaluated for TSH, fasting blood sugar (FBS) and serum triglycerides. The observations and interpretations were recorded and results obtained were statistically analyzed. Results and conclusions: A high prevalence of thyroid dysfunction was observed in type 2 diabetic patients with dyslipidemia. Thyroid dysfunction was more prevalent in diabetic patients, with presence of dyslipidemia and it is a significant contributing factor for metabolic syndrome. The two groups categorized one as Control study (group A) and another as Cases study (group B) for estimation of TSH, TG and FBS. The results were found to be statistically significant with p value less than 0.0001 in all the three parameters. The serum TSH, TG and FBS were profoundly higher in case study group as compared to the normal subjects. Subclinical hypothyroidism needs to be screened among diabetic patients.