Association Of Ischemia Modified Albumin With Glycaemic Status In Type 2 Diabetes Mellitus

Research Article
PriyaPatil., Ashalatha V Rao and Sukanya Shetty
DOI: 
xxx-xxxxx-xxxx
Subject: 
science
KeyWords: 
Hyperglycaemia, Ischemia modified albumin, Glycated Hemoglobin, Diabetes mellitus
Abstract: 

Ischemic modified albumin (IMA) has been shown to be a rapidly rising and sensitive biochemical marker especially for the diagnosis of myocardial ischemia. Data exists showing that IMA is also elevated in patients with diabetes mellitus and many other diseases. In view of the possible association between ischemic modified albumin and type 2 diabetes, the present study was taken up to assess the correlation between IMA and glycaemic status in type 2 diabetes mellitus. A total of 90 subjects(45 diabetes subjects and 45 age and sex matched controls) were included. FPG, 2hr-PG, HbA1c were estimated on autoanalyzer and serum IMA was estimated manually. Results show that high serum IMA and HbA1c were observed in diabetic subjects than in controls. The difference was statistically significant. A significant positive correlation between HbA1c and IMA was present. No correlation was present between duration of diabetes with IMA and HbA1c.