Oral cancer is among the ten most common cancer worldwide and is a significant health problem throughout the world. Early detection and prompt treatment offers the best chance for cure. As patient’s awareness regarding the danger of oral cancer increases the demand for screening is expected to increase. Any tool that improves the early detection of lesions can effectively improvise oral cancer screening system. Many light based noninvasive diagnostic techniques have been developed that aid in the early detection of oral cancer. Among these autofluorescence spectroscopy is emerging as one of the most potential and dynamic tool in the early diagnosis of oral cancer. Here we highlight the importance of the science of autofluorescence spectroscopy in the early detection of premalignant and in situ malignant lesions and the role of stomatologists.
