A Brief Metabolic Study On Biochemical Changes In Blood Of Diabetic Patients

Research Article
Shazia Nazir and Ittagappa M
DOI: 
http://dx.doi.org/10.24327/ijrsr.2018.0911.2875
Subject: 
science
KeyWords: 
Diabetes Mellitus, FBG, liver enzymes.
Abstract: 

Diabetes mellitus (DM) is a major endocrine health problem which occurs due to disturbances in carbohydrate metabolism and results in increased blood glucose levels (hyperglycemia). Diabetes mellitus is either immune-mediated (Type 1 diabetes), resistance (Type 2). Diabetes has a worldwide prevalance with India being the diabetic capital of the world by the year 2030, followed by China and USA. This study was carried out to evaluate the biochemical parameters in diabetic and non- diabetic patients. The measured biochemical parameters were fasting blood sugar, ALT, AST, ALP, triglyceride and total cholesterol. Our study included 50 diabetic and 20 non-diabetic subjects (controls). In this study mean values of fasting blood sugar was found to be higher and significant for diabetic patients as compared to their non-diabetic counterparts. In our study serum levels of all liver enzymes (ALT, AST, and ALP) were found to be significant in patients as compared to controls. Also our study showed significant increase in levels of total cholesterol in patients as compared to healthy controls. No significant difference in serum levels of triglyceride (TG) was observed in patients as compared to controls. The outcomes of the present study suggest that FBG, liver enzymes (ALT, AST, and ALP), total cholesterol have shown higher activity with DM patients than individuals who do not have DM.