Can Bilateral Symmetric Dumbbell Shaped C2 Nerve Sheath Tumors Be Considered As Criteria Of Nf-1?

Ganglioneuroma is rare benign tumors of autonomic nerve fibers arising from neural crest cells. We report a case of 40-year-old male, with features of NF -I, presented us with complaints of gradually progressive quadriparesis for one year and bladder dysfunction. His imaging (MRI cervical spine) was suggestive of bilateral symmetric dumbbell shaped tumor at C2, and multiple similar small lesions at other cervical level. Tumor resection was done and histopathology report was consistent with ganglioneuroma. Out of the 14 cases reported in literature till date, association with NF-1 and multiplicity of lesion was seen. In the post MRI advent era, these features can be considered as one of the minor criteria for NF1.