Posterior Reversible Encephalopathy Syndrome (PRES) is a clinicopathological syndrome associated with various clinical conditions presenting with headache, encephalopathy, seizure and cortical visual disturbances. Radiological findings in PRES are thought to be due to vasogenic edema predominantly in posterior cerebral hemispheres and are reversible with appropriate management. A case of postpartum PRES, 23year old primigravida of 38 weeks period of gestation was admitted to labor room with bleeding per vagina. She was admitted for safe confinement. Caesarean section was performed for fetal distress. On 5th post operative day the mother developed headache, blurred vision and generalized tonic clonic seizures. The provisional diagnosis of postpartum PRES was made and confirmed with MRI. All other causes of postpartum seizures were ruled out. Mother was successfully treated with anticonvulsants, antihypertensive and other supportive treatment. Postpartum PRES is a rare clinical condition mostly associated with hypertension, preeclampsia and vasculitis. Early recognition and treatment can lead to complete recovery of the condition.
