Objective: Management and outcome of pregnancy in Idiopathic thrombocytopenia
Methods: Five pregnant women with Idiopathic Thrombocytopenic Purpura admitted in Lady Goschen Hospital Mangalore, from April 2015 to september 2015, were studied in this prospective study; course and perinatal outcome of pregnancies were studied.
Results: Out of 5 patients with idiopathic thrombocytopenic purpura, 3 were already diagnosed while 2 were diagnosed during present pregnancy. Four patients had severe thrombocytopenia, and one of them showed hemorrhagic manifestation. Four patients required steroids during pregnancy. One patient received immunoglobulin therapy. During the antenatal period one patient developed Eclampsia. She was on steroids in antenatal period. There was no postpartum hemorrhage or maternal death. None of the neonates had bleeding complication, irrespective of mode of delivery.3 patients out of 5 delivered vaginally, 2 by caesarean for obstetric indication.
Conclusion: We conclude that most women with ITP, and even those with severe thrombocytopenia during pregnancy have good outcome. Safe outcome of pregnancy in women with ITP requires teamwork between haematologists, obstetricians and neonatologist. Timely detection and appropriate management has a favourable outcome in thrombocytopenia.