Background: To determine the clinical pattern of infectious keratitis and to identify the organisms responsible for the infection. Methods and Materials: All patients with suspected infectious corneal ulceration presenting to the ophthalmology department, mamata general hospital, khammam, were evaluated. Sociodemographic data and information pertaining to risk factors were recorded, all patients were thoroughly examined. Corneal cultures and scrapings were performed for microbiological examination and appropriate treatment was given. Results: Out of 234 patients 152(64.95%) were males and 82(35.04%) were females. Among all the patients, bacterial keratitis was found in 89(38.03%), fungal keratitis was seen in 84(35.89%) and mixed in 15(6.41%). The most common predisposing factor for infectious keratitis was trauma 131(55.98%). Greater risk of infectious keratitis was seen among agricultural workers which constituted 120(51.28%) cases. Most common bacterial isolate was Streptococcus pneumonia 41(46.06%) and most common fungal isolate was Fusarium 33(39.28%). Most of the bacteria were sensitive to ceftazidime(92.13%), amikacin(92.13%). Conclusions: Corneal ulceration is a common problem in our region and most often occurs after a superficial corneal injury with organic material. The most common bacteria isolated were Gram‑positives, and they were less resistant to ceftazidime and amikacin.
