Background: Pyoderma is pyogenic skin infection caused mainly by Staphylococci and Streptococci are common skin infections presenting to Dermatology clinics. Aim: To study clinical profile, know causative organism(s) and their antibiotic susceptibility pattern. Materials & methods: All out patients & in patients reporting to MediCiti medical college / hospital with pyoderma skin lesions of 100 cases were included in the study. After obtaining consent, detailed clinical history noted. Gram staining was done & the specimens are inoculated for growth on nutrient agar, sheep blood agar and Mac Conkey’s agar plates. The organisms were identified on the basis of morphology & culture characteristics including antibiotic sensitivity. Antibacterial sensitivity testing was done by Bauer Kirby method using Mueller Hinton agar plate supplied by Himedia. The study period was one year. Results: Among 100 cases, primary pyodermas were 66 and secondary pyodermas 34 cases. Bacterial culture shown growth of single organism from 84 cases, 4 cases shown mixed growth & 12 cases no growth. The commonest organism isolated predominantly was Coagulase positive Staphylococcal aureus in 39 cases followed by Coagulase negative staphylococcal organism in 14 cases and other organisms in remaining cases. Coagulase positive staphylococcus aureus isolated was sensitive to antibiotic drugs like Amoxicillin+Clavulanic acid, piperacillin+Tazobactum, Vancomycin, Ceftriaxone, Cefixime and resistant to Lomefloxacin, Ceftazidime, Erythromycin, Cefoxitine, Cefuroxime. Coagulase negative staphylococci were sensitive to Doxycyclin, Amoxicillin+Clavulanic acid, Erythromycin, Cefepime, and Ceftriaxone and resistant to Amoxicillin, Oxacillin, Lomefloxacin & Gentamicin. Klebsiella species shows sensitivity to Ceftazidime / Clavulanic acid, Cefepime and resistant to Ampicillin. Pseudomonas species shows sensitivity to Ceftazidime / Clavulanic acid, Cefepime and resistant to Ampicillin. Conclusions: This study shows the present pattern of bacteriological profile of pyodermas in patients attending MediCiti medical college/hospital. Staphylococcus was most common bacteria causing pyoderma. Therefore pus for culture & sensitivity testing is essential to know causative organisms, drug sensitivity and resistance patterns which can help to select appropriate cost effective antibiotic & also to prevent bacterial resistance.
