Introduction: This study evaluated the sealing ability, marginal adaptation and cost effectiveness of MTA of three different manufacturer’s (MTA Angelus, Medicept MTA, Xenon Bullet MTA) to repair iatrogenic furcation perforations. Material and method: sixty four molars were treated endodontically, perforated in the middle of the pulpal floor and divided randomly into3groups of 20 each, while 4 teeth were used as positive and negative controls. The teeth were embedded in moistened flower sponge, the perforations were filled with respective MTA materials. The teeth remained in the soaked sponge for 28 days and submerged in basic fuchsin solution 1% for 48 hours. Dye penetration was evaluated after longitudinal sectioning of teeth. Result: MTA angelus performed better than other groups. ANOVA Test showed highly significant difference in mean leakage score (F score=10.9,p<0.0001). Tukey post hoc test showed significant difference between group I and III and highly significant difference between group I and II and group I and III. Conclusion: Angelus proved to be the best but the other products like Xenon Bullet MTA has also found to produce equivalent results
