The present study was done on fifty adult patients with chronic periodontitis to assess the effect of locally applied gel containing Chlorhexidine alone and combination of metronidazole and Chlorhexidine as an adjunctive to non-surgical therapy in patient with pocket depth<=7 mm. Following baseline parameters were examined including plaque index (PI), probable probing depth (PPD), Gingival index (GI). The patients were randomly assigned to two groups: Group 1(Chlorhexidine alone) and Group 2(Chlorhexidine plus metronidazole).Scaling and root planning was done one week before investigation. Clinical re-examination was performed at the end of two weeks after application of gel. Results shows that combination of Chlorhexidine plus metronidazole in gel composition could be more effective than Chlorhexidine alone. This study concluded that combined treatment Group 2 showed more improvement in PI, GI and PPD in comparison to Group 1.
