Comparative Studies Of Anti-Inflammatory Properties Of Cymbopogon Citratus (Dc.) Stapf And Piper Longum L. Following Mice Paw Oedema Test

Research Article
Renuka Ballal and Khetmalas M. B
DOI: 
http://dx.doi.org/10.24327/ijrsr.2018.0910.2794
Subject: 
science
KeyWords: 
Carrageenan induced mice paw oedema test, anti-inflammatory properties of Cymbopogon citratus (DC.) Stapf and Piper longum L., inflammation reducing plants.
Abstract: 

Inflammation is a protective mechanism of immune system characterised by secretion of proinflammatory substances like nitric oxide, Interleukin 1, Interleukin 6, TNF-α, Leukotrines, Prostaglandins and vasoactive amines. Though it is aimed towards protection against invading pathogens or neutralization of toxicity precipitated by chemicals; its manifestation is observed in harmful manner. Most of the times it acquires fulminating symptoms due to impaired pathway for production of PRDX5 proteins. On this back ground comparative study of aqueous extract of Cymbopogon citratus (DC.) Stapf and Piper longum L. was carried out with respect to potential antiinflammatory properties. Carrageenan Induced Mice Paw Oedema Test revealed statistically significant anti-inflammatory properties of Cymbopogon citratus (DC.) Stapf.