Background: With the rise in day care procedures, the need for early recovery and stable hemodynamics is must for early discharge of the patient. So, we need agents with faster induction, early recovery with stable hemodynamics, with minimal side effects Material and method: After CTRI registration and ethical committee clearance, a total of 74 patients were taken for the randomized prospective study.Patients were divided into two groups according to the Inhalational agent they received. Patient receiving Sevoflurane (group S, n=37) and Desflurane (Group D, n=37).After taking patient in OT, all the monitors were attached according to ASA guidelines and baseline parameters were recorded.Patient were preoxygenated and induced with Fentanyl 2mcg/kg, Propofol 2mg/kg and Vecuronium 0.1mg/kg. I-gel was secured and Ryle’s tube of appropriate size was passed through the gastric port of I-gel.Continuos monitoring of HR, MAP, SPO2, was done and recorded. After application of last stich, both inhalational and Nitrous were turned of. Recovery was assessed by Time to return of spontaneous respiration, Time to extubation of I-gel, and Time to return of consciousness(by recall of name).Emergence and complications were noted if any. Results: The hemodynamic parameters were comparable amongst two groups. The recovery as assessed by Time to return of spontaneous respiration, Time to extubation of I-gel, and Time to return of consciousness was earlier in Desflurane group, but the data was not statistically significant. Similarly the MAS were greater with Desflurane group as compared to Sevofuranegroup at 5 minutes suggesting earlier recovery with Desflurane. However MAS at 10 minutes were comparable amongst the two groups. The incidence of emergence agitation and complications were comparable amongst the two groups. Conclusion: The Hemodynamic stability is comparable of Desflurane and Sevoflurane, However earlier recovery is better with Desflurane as compared to Sevoflurane, contributing to earlier fast tracking of patients and early discharge. Intermediate recovery is comparable amongst the two groups. Emergence agitation is higher with Sevoflurane than Desflurane but data is not statistically significant. The Complications are comparable amongst the two groups.
