Background: Metabolic derangements of polycystic ovary syndrome (PCOS) are contributing factors of increased the risk of cardiovascular disease. Lipid accumulation product (LAP) index as a cheap and reliable marker of cardiovascular risk and insulin resistance (IR) and metabolic syndrome (MS). Objective: The aim of this study was to estimate LAP index and compare with BMI, body adiposity index (BAI) and waist hip ratio (W/H ratio) in newly diagnosed PCOS patients with controls. Materials and Methods: This is a case-control study including 30 PCOS patients aged between 15 and 40 years and 30 age matched healthy controls. Fasting sample were obtained for lipid profile analysis after getting written consent. Anthropometric measurements were taken as per protocol. LAP index, BMI, BAI and W/H ratio were calculated and analysed statistically. Results: Among PCOS patients, LAP score had significantly positive correlation with patient’s age (r = 0.42 & P=0.02), BMI (r = 0.441 & P=0.015), BAI (r = 0.45 & P=0.013) and W/H ratio (r = 0.405 & P=0.026). Among controls, LAP score had more significant positive correlation with W/H ratio (r = 0.546 & P=0.002). LAP score and W/H ratio had highly significant P value (P= 0.000) and BMI showed P= 0.003 while comparing PCOS patients and controls. Conclusion: LAP index, an easily obtainable, reliable, cheap marker of cardiovascular risk, IR and MS. The early deduction and intervention could be possible to prevent metabolic and clinical complications among PCOS patients by LAP scoring.
