Background: There is a resurgence of dengue fever in the recent times due to the multitude of changes in environment. During the last rainy season there was again an outbreak of dengue fever in kerala and Calicut medical college was one of the main tertiary care centres where serious cases were refered and treated. Materials and methods: All patients admitted to medicine wards with short duration fever and with dengue NS1 antigen positivity were taken up for study. The patients were subjected to clinical examination and baseline clinical investigations accordind to a detailed proforma. Results: The total number of cases were 202 patients of which 146 were males (72.3% and 56 were females (27.7%). The most common symptoms high grade fever, rash, polyarthralgia, myalgia headache vomiting. Leucopenia was seen in majority of patients 143(71%). Severe thrombocytopenia (platelet count<10000) was seen in 13% (27) patients. 23(11%) of the patients had DHF diagnosed by WHO criteria of which 4 died.4 (1.9%) patient had DSS of which all the patients died. Hepatitis in the form of elevated liver enzymes were seen in 189 (89%) patients. All the patients who expired had very high liver enzymes. all the four patients who died has hypotension, fulminant hepatic failure serosistis and hemoconcentration and severe thrombocytopenia.
