Microorganisms from marine environments have high diversity with millions of varied species in producing naturally bioactive metabolites like terpenes, quinones, xanthones, coumarins and isocoumarins, chromones, aflatoxins and alkaloids. In point of ecological and biotechnological view current research is sighting in to development of new drugs from marine region which is still attracting the researchers. Fungi are heterotrophic eukaryotes play an ecological role in the decomposition of plants and to a less extent on animal tissues that leads to the release of nutrients back into the ecosystem. The fungal isolates from marine environments are a source of novel and potential bioactive secondary metabolites, which are life-saving like antibacterial, antifungal, antiviral, antiprotozoal and anticytological compounds playing a possible role in disease suppression. More than 23,000 secondary bioactive metabolites are reported out of 17,000 antibiotics were discovered from microorganisms. This review focuses mainly on Marine fungi and its natural products in drug discovery and various isolating techniques to carry out production of potential bioactive compounds.
