The irrigation of the root canal system contributes effectively to a clean and appropriate antisepsis more predictable success of endodontic treatment. An ideal protocol irrigation was suggested in order to overcome the limitations of commonly used irrigation and enhance antisepsis. This protocol is recommended the use of sodium hypochlorite for biomechanical preparation, followed by a final chelating agent. EDTA chelation is used worldwide in this role today; however there is a lack of current literature review of studies of the same, as many irrigating solutions have been developed in order to improve the final irrigation protocol. Thus the purpose of this review is to lead to different clinical indications of use as well as bringing considerations of effectiveness, biocompatibility and influences the dentin surface of the irrigating solutions.
