A The nutritional diet is one of the important external environmental factor that affects on the growth and development, stress resistance , survival ability, reproduction and also alters the sex ratio. In the present study the flies of Drosophila melanogaster were cultured in the wheat cream agar media, mixed and Ensure® media, to understand the effect of ensure nutritional supplement on the sex ratio in Drosophila melanogaster. The results revealed that, female offspring were more than the male offspring in all three diets. The Ensure® media flies produce more male and female offspring compared to control and mixed diets. Thus it suggests that nutritional dietary components in the food alters the offspring sex ratio in Drosophila melanogaster.
