Background: A tooth during the normal course of its function is subjected to several stresses, the chief amongst which is the flexion generated on mastication. An endodontically treated tooth looses elasticity and hence materials which are used for obturation and post-endodontic rehabilitation of such teeth, need to replicate the Flexion of the tooth. Push Out Bond Strength (POBS) is an accurate way to assess the longevity of Root Canal Therapy. Objectives: To analyze the effect of various Pre-Obturative protocols on the Push Out Bond Strength of MTA-based sealers. Data Sources: English language articles were retrieved from electronic biomedical journal databases. PubMed, Google scholar and Research Gate were used to complete the search for all full text articles available. The search was done till 31st August 2016. The last data search was conducted on 1st September 2016. Study Eligibility Criteria: All articles that were published in English were included. Only those articles that were published between 1st January 2000 and 31st August 2016 using MTA based Sealers were selected. Intervention: Effect of various Pre-Obturative protocols on the POBS of MTA based sealers. Results: Total of 34 articles were identified through electronic database searching. After duplicate removal, and full text reading, 13 articles qualified for qualitative synthesis in this systematic review. Limitations: Few articles do not clearly mention the values of POBS which makes the interpretation difficult. Conclusion: Procedures that are done routinely prior to the use of MTA as a sealer are found to affect the POBS.
