Research findings of A study to assess the efficacy of normal saline and chlorhexidine mouth wash in prevention of oral mucositis among patients undergoing radiation therapy at radiation oncology ward, SVIMS, Tirupati was undertaken to reduce the complications of radiation therapy. The study findings reveals that in normal saline group the mean pre interventional oral mucosists intensity was 0.240 with SD of 0.650 and the post interventional mean was 1.293 with S.D of 1.743 and the paired ‘t’ value obtained was 4.266 which is significant at P<0.01 level. In chlorhexidsine group the pre interventional mean obtained was 0.280 with S.D of 0.776 and the post interventional mean was 0.620 with S.D of 1.181 and paired t value obtained was 1.743 which is statistically not significant. When comparing the post interventional mean of normal saline group is 1.293 with S.D of 1.743 and the mean in chlorhexidine group is 0.620 with S.D of 1.181 and student ‘t’ value obtained was 2.260 which is statistically significant at P<0.01 level. These findings indicate that there was significant reduction in oral mucositis among patients receiving chlorhexidine mouth wash when compared with normal saline mouth wash.
