This study was aimed to find the Epidemiology of trauma patients admitted in emergency surgical ward with special reference to prognosticate by serum. This was an observational study conducted on the patients admitted to trauma in emergency ward, Department of General Surgery, King George Medical University, Lucknow, India. A total of 604 patients with various HIs and polytrauma – burn, assault was studied in detail on a predesigned proforma, and follow up data were also recorded. Age is the most consistent variable defining differences in head injury rates, with highest incidence in 21-30 years. Male patients are significantly higher than female patients.Mortality was higher in rural population as compared to urban population.Private vehicles are used in majority of cases to bring the patients to trauma centre and mostly from rural areas. The serum LDS levels correlated with both the severity of head injury as judged by Glasgow Coma Scale as well as the prognosis of the patient. Serum LDH levels were found to be higher in non survivors than survivors among all three groups of patients based on their GCS Scale and the difference was found to be statistically significant (p0.05). Serum LDH provides an excellent objective parameter to judge the severity of head injury. Although it cannot replace the excellent clinical GCS scale it still serves to provide additional information along with GCS scale especially in patients in whom GCS is rapidly fluctuating or sedated patients in which GCS cannot be assessed.