For a safeguard and a valorization of ancestral knowledge on the medicinal plants most used in traditional pharmacopoeia in the treatment of the diseases of the digestive system, an ethnobotanic study was carried out near the riverine population of the forest of Izarène, (North-East of the town of Ouezzane). By using 520 questionnaires, and during three programs of terrain (2007-2010). This study enabled us to count 62 exploited species, divided into 31 families and 59 genres. The families best represented are Lamiaceae, Apiaceae, and Fabaceae. The gotten results showed also that the aerial part is the most used. The infusion is the mode of preparation dominating and the administration is done mainly by oral way. Among the 62 medicinal species used by the riverine population, 20 spontaneous species are collected from the forest of Izarène. The overexploitation threatens some species little abundant like Mentha rotundifolia, Origanum compactum, Centaurium Erythraea, and Solanum nigrum of disappearance from the forest of Izarène. Hence the interest to adopt a sustainable approach of management to ensure the conservation and the preservation of these species. In addition, among the noted species, some are recognized by their toxic capacity such as Nigella sativa, Zygophyllum gaetulum and Artemisia herba-alba. The results obtained could constitute a data base from the point of view of the phytochimical and pharmacological experiments and of the implementation of the innovating initiatives being able to lead to the manufacture of the traditional drugs used in the treatment of the diseases of the digestive system
