The present study was carried out to evaluate the anti ulcer potential of ethanolic leaf extract of Cardiospermum halicacabum Linn. against Indomethacin induced gastric ulcer model in male Wister rats. The ethanolic extract of C. halicacabum (EECH) was administered at a dose of 200 and 400mg/kg orally 30 min. prior to ulcer induction. Omeprezole (10mg/kg/day p.o) was used as a standard. The anti ulcer activity was assessed by determining the ulcer index in the test group along with the Standard drug treated group. EECH registered a significant dose dependent decrease in the extent of gastric mucosal damage in the induced ulcer models. Presence of bioactive compounds like flavonoids, tannins, phenols, saponins and caffeic acid may be responsible for the anti ulcerogenic activity of the present study plant.
