Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycaemia generally associated with oxidative stress. The present study aims at evaluating the antioxidant and antidiabetic potential of methanol extract of the corm of Hypoxis hemerocallidea (MEHHC)commonly known as the ‘African potato’. The study was conducted in two different secessions and first part estimated the antioxidant status and the second part was assessing the anti-diabetic properties The in –vivo study was designed to check the anti- hyperglycemic effect of the extract on a weekly basis and the other parameters checked at the end of the experiments were the liver markers lipid profile and other glycemic indices. The results of the first session showed higher levels of antioxidant status and the in-vivo studies showed the anti-hyperglycemic effects of the extract. This was comparable to the effect of the anti-diabetic drugs used for the treatment of diabetes. The overall study indicates that MEHHC is effective in controlling the diabetes through its antioxidant system
