Evaluation Of Orthobiologics For Management Of Avascular Necrosis Of Head Femur: An Innovative Surgical Technique

Research Article
Ajai Singh., Ekansh Debuka., Vineet Kumar and Sabir Ali
DOI: 
xxx-xxxxx-xxxx
Subject: 
science
KeyWords: 
Aseptic osteonecrosis; Femoral head; Bilateral core decompression; Stem cell.
Abstract: 

In this prospective study, total 13 patients of idiopathic avascular necrosis of head femur with 20 affected hips were managed by core decompression and autologous bone marrow derived stem cell infusion. Bone marrow aspiration was followed by mononuclear cell separation and then subsequently injecting the same up to the necrotic area of the femur head. These patients were followed up clinico-radiologically at 3rd, 6th, 12th, and 24th weeks and at one year post operatively. In this study, we observed significant improvement in pain at one year follow-up as per VAS. Improvement of trendelenburg gait and range of movement at final follow-up were significant. Harris hip score during follow-up improved significantly. Core decompression and stem cell infusion is one of the less traumatic viable alternate treatment options for management of idiopathic avascular necrotic head femur.