Background- MRSA infections are become a growing problem in community as well as challenge for healthcare facilities. Community acquired methicillin resistant Staphylococcus aureus (CA- MRSA) is a major global problem. Aim- to evaluate the presence of PVL toxin gene as a sole marker to validate the genotypic definition of the CA-MRSA isolates. Material and methods: 210 S. aureus strains were included in this study. 100 MRSA isolates identified by phenotypically using Cefoxitin disc diffusion test. Molecular detection of mec-A gene and PVL gene was done by PCR method. Results- We found that PVL toxin gene was present in 62/100 (62%) among all MRSA. Out of these 42/58 (72.41%) were CA-MRSA and 20/42 (42.61%) isolates were HA-MRSA. Conclusion- The present study suggested that the presence of the PVL toxin gene cannot be used as a reliable marker for the CA-MRSA infections.
