The cocoons of silkworms consist of two major proteins a hydrophobic fibroin and hydrophilic sericin. The fibroin protein recognized as biomaterial for various biomedical applications as surgical sutures, hydrogels, scaffolds and nanoparticles as a drug delivery vehicle in addition to textile uses. Silkworm produces a large amount of sericinat the end of fifth instar along with the fibroin and form the silk thread used in the construction of the cocoon, which provides the ideal conditions for the larval metamorphosis to adults. The silk textile industries discardsericinas waste after degumming process. But recently research is initiated on biomedical applications of domesticated Bombyxmori silk sericin whereas Indian tropical wild tasar silk proteins related research is still in juvenile stage. Hence in present study we extracted the sericin and evaluated its antimicrobial potential from Tasar silkworm Antheraeamylitta on pathogenic bacterial strains of Escherichia coli, Staphylococcus aureus and fungal strains of Candida albicans, Aspergillusflavus.
