This study investigated the factors militating against the delivery of quality of nursing care in University of Port Harcourt Teaching hospital (UPTH). Two specific objectives guided the study. The population consisted of all the 65 nurses working in Children wards/units during the period of study. A self structured questionnaire was used to collect data. Validity of the instrument was ensured, reliability was ascertained using test re-test method, values were analysed using Pearson product moment correlation with a value of 0.92. Data obtained were analyzed using figure, frequency and percentage table. Results revealed that out of the 65 respondents studied, 12(19.4%) had poor knowledge, 14(21.5%) had fair knowledge while 39(59.1%) had good knowledge regarding the concept of quality nursing care. The factors identified as militating against the delivery of quality nursing care involves both personnel and service setting factors which included; nursing shortage rating 19(29.2%), personnel problems 15(23.1%), lack of resources and equipment 10(15.4%), poor unsupportive work environment 9(13.8%), lack of continuous education and training 8(12.3%,),and intra/inter-professional rivalry 4(6.2%). Some of the recommendations based on the findings includes; -Nursing staff should be well informed on how best to effectively utilize available resources to provide quality nursing care, quality assurance should be regarded as an integral part of health care and should become rooted in hospital management, there should be constant supervision of the nursing staff and subordinates by nurse managers.