Breast cancer is the most frequent women cancer and is their first cause of cancer death. . This cancer is mostly sporadic, but familial aggregation was found in about 20% of cases. It is a heterogeneous disease with several subtypes.
This is a cross-sectional study gathering 1277 breast cancer cases supported between 2013 and 2014 at the Mohammed VI Center for the treatment of cancers. The statistical analysis was made by the Epi Info software.
The average age of patients was 50.2 ± 11,34ans (17-93 years). The notion of family history of breast cancer was in 13.5% of cases. Triple negative molecular profile was in 16.4% of cases and 83.6% were non-triple negative. The age of breast cancer occurred was younger in cases with a family history of breast cancer (48.5 ± 10.5 years vs. 50.4 ± 11.4 years) than patients without family history (p = 0.03). TN patients showed a younger age (47.9 ± 11.7 years versus 50.0 ± 10.9 years) than non TN patients (p = 0.03).
A family history of breast cancer has been proposed as one of the most important predictor of hereditary breast cancer. The TN breast cancers are associated with a worse prognosis and represent 16.4% of cases in our center.
