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The aim of the study was to perform in vitro phytochemical screening, Quantitative estimation and free radical scavenging activity of various extracts of the plant Ecbolium viride (Forssk).Alston belonging to the family Acanthaceae. It is a perennial woody shrub commonly known as Green Shrimp plant. Traditionally different parts of the plant like roots, leaves, stem and whole plant are used in folklore medicine for several medicinal purposes like cancer, jaundice and rheumatism.The preliminary phytochemical screening revealed the presence of various phytoconstituents, in vitro free radical scavenging activity of various crude extracts were determined using DPPH, Hydrogen peroxide, and reducing power assay. The present investigation was designed to evaluate the in vitro phytochemical screening, antioxidant activity of the extracts was compared with standard antioxidants and the dose dependent response was observed in reducing power of extracts. The findings suggest that E. viride exhibited potential in vitro free radical scavenging activity.