Introduction: There is a substantial increase in the coincidence of diabetes mellitus and cardiomyopathy. The cardiomyopathy may occur in patients who have no evidence of large vessel disease or abnormalities.
Aims:The present study was undertaken to assess the prevalence of diastolic dysfunction in patients with type 2 diabetes and to assess the correlation of diastolic dysfunction and HbA1c% levels
Materials and Methods: A total of 100 diabetic patients with minimum 5 years duration of diabetes were selected from Gandhi Hospital attached to Gandhi Medical College Secunderabad between June 2014 and June 2015 and were scrutinized for Doppler echo cardiography and HbA1c levels.
Results: Diastolic dysfunction of left ventricle was observed in 59 patients out of 100, of which 47 (79.66%) patients had HbA1c% of > 7. 8 (13.5%) patients belong to HbA1c% group of 6.1-7 and 4(6.7%) patients belong to HbA1c% of <6.
Conclusion: Our findings indicate that myocardial damage in patients with diabetes affects diastolic function before systolic function.Even young patients with diabetics with normal systolic ventricular function have diastolic dysfunction, which serves as a marker of a diabetic cardiomyopathy. Diastolic impairment seems not to correlate with disease duration. HbA1c% can be a very good indicator of long term prognosis. Strong correlation exist between diastolic dysfunction and HbA1c%.
Sastry K.B.R et al.2016, Glycosylated Hemoglobin And Left Ventricular Diastolic Dysfunction In Patients With Type 2 Diabetes Mellitus. Int J Recent Sci Res. 7(10), pp. 13839-13843.