With improvement in living standard in our country a Hand Wash is becoming a popular and important product. The special feature of Hand Wash has acidic pH 5-6 which match with our skin and Antimicrobial activity against several microorganisms. Liquid glucose also known as Corn Syrupis a fundamental ingredient in many food and industrial products it is a purified concentrated aqueous solution of nutritive saccharides obtained from starch. The quality of liquid glucose has a direct impact on the quality and performance of the finished product. In the present research work polymeric surfactant is prepared using liquid glucose and sorbitol. This polymeric surfactant is used in preparation of hand wash. The Antimicrobial Activity of our Hand Wash was tested against S. auerus and E. coli. The Minimum Inhibition Concentration is 0.125 mg for both type of microorganism. The hand wash prepared from liquid glucose polymer appears to have excellent microbial activity
