This paper analysis relation andimpacts of Islamicity on happiness, with human development and global competitiveness as moderating variables.Cross-nations data on Islamicity, human development, global competitiveness and happiness were collected from 123 countries and employed in a path analysis model. The result showed that there were positive and very strong correlations between Islamicity and happiness (r14= 0.81), between global competitiveness and happiness (r34= 0.76), and between human development and happiness (r24= 0.82). Path coefficients indicated that direct impact of Islamicity on happiness was positive and significant (P41= 0.36), direct impact of global competitiveness on happiness was positive and significant (P43= 0.06), direct impact of human development on happiness was positive and significant (P42= 0.46). Indirectly, the impact of Islamicity on happiness, through global competitiveness was positive, but statistically not significant (P43-P31= 0.04), the impact of Islamicity on happiness through global competitiveness and human development was positive, but statistically not significant (P43-P32-P21= 0.01) and the impact of Islamicity on happiness through human development was positive and significant (P42- P21=0.39). Implication of this finding was that applying Islamic teaching and implementing the practice of human development would be very important to make people happy and to maintain happiness.