Incidence Of Nasal Colonization By Community-Associated Methicillin-Resistant Staphylococcus Aureus (Ca-Mrsa) Infection During 2000 To 2017

Research Article
Knop, L., Santana, LSG and Carvalho, TF
Methicillin-resistant Staphylococcus aureus (MRSA), Community-associated MRSA (CA-MRSA), nasal colonization by S. aureus.

Staphylococcus aureus (S. aureus) is a spherical microorganism, Gram-positive cocci, and common bacterial flora, considered an opportunistic human pathogen that can cause a large number of infections. The skin and nasal mucosa are the site concentrations of these bacteria in humans. S. aureus infections were treated with penicillin originally, however, new resistant strains emerged and beta-lactam, such as methicillin, was an antimicrobial of choice. However, multiresistance is a current reality and there are a lot of reports of methicillin-resistant Staphylococcus aureus (MRSA), followed by some reports of vancomycin resistant of S. aureus (VRSA). The occurrence of MRSA was restricted to the hospital (HA-MRSA), but with the emergence of resistant strains and the transport of bacteria by carrier individuals’ nosocomial to community it started to colonize and infect health people in community. This study aims to correlate the incidence of nasal colonization and infection by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in the period of 2000 to 2017 through representative studies of current literature in order to bring new findings in the literature. The research was made in international databases of scientific articles from 2000 to 2017. In the present study, only nasal colonization incidence was selected. It was possible to observe that there was an increasing in the spread of this strain in the community in this period. Our data reinforce the hypothesis that the increase of CA-MRSA nasal colonization rates may contribute to the development of severe infection cases. However, more studies are necessary with a larger number of samples to prove and evaluate the causal association of this dissemination in the community and the incidence of nasal colonization and infection by CA-MRSA.