The myth that the atherosclerotic vascular disease (ASVD) has a hereditary or purely nutritive origin is not true. Recently this coronary heart disease is also possibly known to have an infectious etiology. Studies have proved to have a correlation between periodontal disease and coronary heart disease. However, till date, there is minimal information relating to this invasion on periodontal pathogens causing coronary heart disease. Studies are conducted to test the hypothesis that invasion of the coronary artery cells by oral bacteria may start and/or exacerbate the inflammatory response in atherosclerosis. This review thus elaborates the possible molecular mechanisms involved in the interactions between periodontal pathogens and cardiovascular (CV) tissues with a focus on invasion of the cells of the arterial wall. And also determines the role of periodontal pathogens in the cardiovascular disease.
