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Aim: To assess the knowledge, attitude and Practices of Infection Control Protocol amongst Dental Postgraduate Students in a Dental College in Pune, India- A cross-sectional Questionnaire based study. Material and Method: Study designA cross sectional study was carried out using a closed ended, self-administered questionnaire consisting of 15 questions in a dental college in Pune, Maharashtra. In all 35 of the 43 post graduate students of the dental college participated in the study giving a response rate of 81.40% Results: The responses received was entered into an Excel spreadsheet, knowledge based questions were analyzed and scored as ‘1’ for each correct answer and mark ‘0’ for each wrong answer as per the responses obtained. Mean and standard deviation of the total knowledge scores was analysed. The result was analyzed using the Statistical Package for the Social Sciences (SPSS; Version 17.0 for Windows 7 OS, SPSS Inc., Chicago, IL). Conclusion: Within in the limitations of the present study it can be concluded that the knowledge of the PG students regarding the infection control is poor, especially regarding the waste disposal.