Introduction:- Oral Lichen Planus is a chronic autoimmune, mucocutaneous disease of unknown origin. It is premaligant condition which has poentency for malignant transformation. Intraorally it affects mainly in buccal mucosa. Women are more affected. and has classical clinical signs and symptoms. The disease is caused by an abnormal cell-mediated immune response. Material & Methods- Out patients visiting the department of Oral Medicine and Radiology, Coorg Institute of Dental Sciences, Virajpet in the age range of 30-50 years old males.25 cases and 25 controls. Proper selection of subjects were done using certain inclusion criteria. Lsions were biopsied and were subject to histopatological examination. Serum cretinin was estimated in blood samples and the findings were recoded.
Results: -. In comparing the values the cases showed increase in all values when compared to healthy subjectsthe study could not establish a stistical significance.
Conclusions:- A biomarker can be used for potentially malignant disorders to know their progression.
