The Study Of 15 cases of Localized form of gigantism in different congenital conditions was carried out in Mmcri, Mysore, Kims Hubli, and Esic Kalaburagi during The Last 30 years. Here patients werre mainly seeking medical advice for cosmetic reasons & for disability certificates. We took clinical photographs, plain radiographs of affected limb, USG (Gray scale & Doppler-showed soft tissue thickening & no Increased blood flow).& biopsy of tissue. Some patients refused for the same. In all the above cases there was abundance of fibrofatty tissue along with dense fibrous tissue, in few cases especially upper limb, nerves were enlarged &thickened. It was confined to
MEGAFOOT- 4 Cases Since Childhood, Stretched Shiny Scaly Dry Skin, Double The Girth Of Opposite Limb Syndactyly (2 & 4TH) TOE, Rudimentary(1ST& 5TH TOE Variation)
Unilateral giant lower limb -2cases
Giant upper limb- 3 CASES
Radial Mega Hand
Mega Thumb-3 cases
Macrodactaly of Index Finger etc……
It Was Compatible With Normal Life.
We Concluded that it is a rare type of disease. No genetic involvement, any theories cannot be formred or dimissed. Few were associated with Neurofibromatosis.
HPE: Excessive Proliferation & Accumulation of Fat is the basic lesion. Surgical correction is the treatment of choice.
Nizamoddin M K. 2016, Localized Gigantism: Series of 15 Cases. Int J Recent Sci Res. 7(10), pp. 13820-13822.