Introduction: One of neglected tropical diseases, geo-helminthiases, currently recognized as an extremely preoccupying ongoing public health problem. In DR Congo, the Mebendazole therapy coverage rates and its incidence are less documented. The aim of this study was to assess the Mebendazole therapy coverages of children under age five years in proportion to the ongoing mass strategy. Methods: This is a cross-section descriptive study conducted in children under age five in the town of Lubumbashi in DR Congo; all the structures whether public or private and children under age five were randomly selected. The studied parameters were: the proportion; the coverage rates and the incidence rates. Results: Out of a total of 12, 592 examined children under age range of 6 to 59 months, we registered 6, 571 who were diagnosed and submitted to Mebendazole; out of a sample of 46, 130, the following cover ages were found : 106.85% in 2012 ; 102% in 2013, 100% in 2014, 101% in 2015 ; 101% in 2016. And 10.3% of parents of children under age five and 17% of the population appreciated the organizational aspect of the mass Mebendazole distribution campaign. In all 6, 571 treated cases; only lumbricoidascarid was identified as a parasite with the highest prevalence 17.68%. Incidences rates during the last five years reveal inferior to 20% i.e. respectively: 15.6% in 2012; 15.5 % in 2013; 15.9% in 2014 ; 16.3% in 2015 and finally 16.8% for2016. Conclusion: From these results stemming from this study we gather that geo-helminthiases remain one of the causes of parasitory infections concerning public health; it is thus important to make significant inquiries for the improvement of the strategy already implemented in order to reduce their parasitory charge arising from geo-helminthes.
