Echiumvulgare known as viper's bugloss is a species of flowering plant in the borage family Boraginaceae. Echiumvulgare was investigated in terms of phenoliccontents and antioxid ant capacity in present study. Antioxidant activity of methanolic extract was examined by two methods, namely ferric reducing antioxidant power (FRAP), and 2,2-diphenylpicrylhydrazyl radical scavenging (DPPH)activity. The phenolic compounds were determined by reverse phase-high performanceliquid chromatography (RP-HPLC). Benzoicacid, chlorogenicacid, caffeicacid, and gallic acid were determined as main phenolic compounds in the methanolic extract. The IC50valuefor DPPH assay has been found as 0.1430±0.0014 (mg/mL), FRAP value is 795±14.1892 (μMTrolox/g sample), and total phenoliccontent value is 10.5±0.1732 mg gallicacidper gram sample in methanolic extract of the aerial parts of Echiumvulgare. Themethanolicextract of Echiumvulgare containsrichphenolic compounds, and potent antioxidant activity that might be used as raw material by pharmaceutical and food industries for the preparation of natural drugs.
