Chlorpyrifos Induced Histological Changes In The Liver Of Tilapia (Oreochromis Mossambicus)

Research Article
Muttappa K, Reddy, H.R.V., Padmanabha, A.,Shridhar Bhatt,Prabhudeva. K.N., Basavaraju, Y., Gangadhar Gowda, Rajanna, K. B., Chethan, N
DOI: 
xxx-xxxxx-xxxx
Subject: 
science
KeyWords: 
Histology, Chlorpyrifos, Lethal toxicity and Oreochromis mossambicus
Abstract: 

A bioassay was conducted to determine the lethal toxicity (LC50) of commercial grade Organophosphate insecticide, Chlorpyrifos (20% EC) on Tilapia (Oreochromis mossambicus). The 96 h (LC50) for Chlorpyrifos (20% EC) was found to be 0.022 ppm. For sublethal toxicity study, the fishes were exposed to two sublethal concentrations (i.e 1/5th of LC50 and 1/10th of LC50) for 21days. Histopathological changes in liver ranged from vacuolization, necrosis, aggregation of melanomacrophge, increase in number of kuffer cells at different time of exposure viz. 7, 14 and 21 days.

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