Diabetes Mellitus is metabolic disorder characterized by excessive glucose in blood circulation mainly resulting from inadequate insulin secretion, insulin action or both and insulin resistance. Gymnema sylvestre have reported beneficial effect for treating in type 2 diabetes mellitus. Objective: Effectiveness of homoeopathic medicine gymnema sylvestre in type 2 diabetes mellitus. Material and method: 60 cases of type 2 diabetes mellitus were selected and gymnema sylvestre was prescribed for these cases and follow up was every one month, three months, six months and nine months. Results: Over a period of nine months, there was significant reduction in blood sugar levels (fasting and post prandial blood sugar) in test group compared to controlled group. ANOVA repeated measures also showed significant difference P = 0.001. Conclusion: There is significant reduction in fasting blood sugar, post prandial blood sugar levels of test group (Gymnema sylvestre) compared to control group (Placebo) in type 2 diabetes mellitus cases.
