Background: This paper describes a new surgical technique for Oro Antral Fistula closure using guided tissue regeneration membrane & bone substitute sandwich technique. Method: 24 patients with oro antral fistula were selected. BIOOSS granules were sandwiched between collagen sheets thus creating a closed sandwich. Following fistulectomy mucoperiosteal flap was raised & the sandwich was than tucked in the sinus with smooth surface facing the sinus & rough surface facing oral mucosa. The mucoperiosteal flap was than sutured over the defect. Patients were followed up for swelling, infection, graft failure & healing, by clinical & radiographic methods. Results: Out of 24 patients objective healing as well as radiological evidence of healing was observed in 18 (100%) subjects. 6 cases of graft rejection was seen due to patients negligence, however overall success rate of the study was 75 %, statistically. Conclusion: This technique yields a more promising closure of oroantral communication by providing a biologically apt base with bone structure at the floor of the maxillary sinus. The reconstructed bony tissue regenerated from this technique is also capable to receive an endosseous implant in the future.
