Objective: A patient of ischemic coronary artery disease (IHD) with additional carotid artery stenosis (CAS) has been distinguished as a high risk group for both heart and cerebral inconveniences following surgical intervention. To break down the outcome of our study with a combined technique through off-pump coronary bypass grafting (OPCABG) and carotid endarterectomy (CEA) in a patient with both Ischemic heart disease and carotid artery stenosis. Materials and methods: Fifteen patients experienced OPCABG and CEA associatively in the vicinity of 2014 and 2016. Six (40%) patients had a past history of myocardial infarction (MI), Four (26.66%) had unstable angina (USAP), and Three (20%) had USAP together with MI, though two (13.33%) were asymptomatic. Nine (60%) patients demonstrated no neurological manifestations, three (20%) had transient ischemic assaults (TIAs), two (13.33%) experienced stroke, and 1 (6.66%) experienced both. Majority 7 (46.66%) patient have 75-90% Carotid artery stenosis and 6 patients experienced right (40%), though 8 (53.33%) experienced left and 1 (6.66%) had bilateral CEA. Five (33.33%) patients were found Left main disease (>50% lesion) and 100% patients have had significant LAD lesion in this study. Twelve (80%) patients show significant lesion in RCA and ten (66.66%) patients had OM disease. CEA was performed before OPCABG in all cases. Result: There were 15 patients (mean age 62.5±2.8 years; 80% were male). Two (13.33%) had a perioperative stroke while One of them had TIAs (6.6%). Mean ICU stay was 36.6±4.5 h and patients were released in 10 days. There was no mortality in the early postoperative period and co-morbidity was less significant (6.6% myocardial ischemia, 13.33% Atrial fibrillation, 6.66% TIA, 13.33% Stroke). There were 1 (6.66%) postoperative Acute renal failure was reported by serum Creatinine levels. Two (13.33%) patients showed respiratory complications; only 6.6% of them were suffered for wound infection. Conclusion: A combined strategy by means of OPCABG with CEA is by all accounts safe and savvy in view of the satisfactory consequences of morbidity and mortality rates and also short ICU and hospital stay status
