post vaccination bcg-osis: an expression of primary t- cell immunodeficiency

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National Academy of

Agricultural Sciences (NAAS)

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*3.65 (2020)

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March-2024

Research Article

Pranati Mohanty, Shilpy, Shushruta Mohanty and Aparajita Das

DOI:

xxx-xxxx-xxx

Subject:

Medical

KeyWords:

BCG-itis, BCG-osis, Immunodeficiency

Abstract:

Introduction: BCG (BacilleCalmette-Guerin) – a live attenuated vaccine is routinely given to neonates where tuberculosis is endemic. Immunodeficient individuals are at a high risk of developing BCG related complications like BCG-itis or BCG-osis.

Case summary: A six month old baby who was vaccinated with BCG at birth developed an abscess at the vaccination site with regional adenopathy with disseminated BCG-osis. He was found to have T-cell immunedeficiency after thorough investigation.

Conclusion: Dissemination following BCG vaccination warrants prompt investigation to rule out primary immunodeficiency in HIV seronegative individuals

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